zambia high demand mbt 2-mercaptobenzothiazole powder
zambia high demand mbt 2-mercaptobenzothiazole powder
zambia high demand mbt 2-mercaptobenzothiazole powder
zambia high demand mbt 2-mercaptobenzothiazole powder
zambia high demand mbt 2-mercaptobenzothiazole powder
  • What is 2 mercaptobenzothiazole?
  • What is 2-Mercaptobenzothiazole? 2-Mercaptobenzothiazole (MBT) is an industrial chemical that is used principally in the manufacture of rubber. What were the results of the IARC Monographs evaluation of MBT?
  • Is 2 mercaptoben-zothiazole a rubber additive?
  • Rapid and sensitive LC-MS-MS determination of 2-mercaptobenzothi-azole, a rubber additive, in human urine. Anal Bioanal Chem, 407(12):3417–23. doi:10.1007/s00216-015-8533-5 PMID:25701422 GuideChem (2015). CAS No. 149-30-4 (2-mercaptoben-zothiazole (MBT)).
  • How much mercaptobenzothiazole is produced in the USA?
  • The United States Environmental Protection Agency (EPA) noted that 500 000–1 000 000 pounds/year [~227–454 tonnes/year] of 2-mercaptobenzothi-azole were produced, imported, and used in the USA in 2012 (EPA, 2012). In 2012, three facili-ties in three states were listed as manufacturing 2-mercaptobenzothiazole in the USA (HSDB, 2015).
  • Are mercaptobenzothiazole derivatives cytotoxic?
  • 2-Mercaptobenzothiazole derivatives were also identified, showing interesting cytotoxic effects in cancer cell models. In these molecules, amide and sulfonimide groups were inserted, obtaining compounds targeting different targets, such as PPARα, CA IX, and tubulin.
  • What is 2-mercaptobenzothiazole used for?
  • 2-Mercaptobenzothiazole is principally used as a reactant in the manufacture of rubber prod-ucts, but is also used as a corrosion inhibitor in oils, greases and cooling fluids. It is added to polyether polymers as a stabilizer to resist damage by air and ozone, and is a component approved in the USA in some skin medications for dogs (HSDB, 2015).
  • Are 2-mercaptobenzothiazole derivatives good antiproliferative in gastric cancer?
  • A very recent work by Song and coworkers identified novel 2-mercaptobenzothiazole derivatives displaying good antiproliferative activity in gastric cancer . The authors designed compounds as potential colchicine binding site tubulin inhibitors and as activators of Hippo pathway.